All subjects with a current diagnosis of asthma

The proportion of subjects reporting respiratory symptoms was higher in grape farmers than in control subjects . After using a multiple logistic regression model and adjusting for age, sex, and smoking status, the differences remained statistically significant for rhinorrhea (OR, 2.7; 95% confidence interval [CI], 1.5 to 5.1; p < 0.001), sneezing (OR, 2.2; 95% CI, 1.2 to 4.0; p < 0.01), and nasal itching (OR, 1.9; 95% CI, 1.0 to 3.6; p < 0.05). Concerning the asthma-related symptoms (ie, dyspnea, wheezing, wheezing with breathlessness, being awoken by cough, being awoken by shortness of breath Viagra in Australia, being awoken by chest tightness, and attack of asthma), there was a tendency toward increased prevalence rates in grape farmers, but this increase was not statistically significant. The prevalence of allergic rhinitis was found to be 40.8% for grape farmers and 26% for the control subjects (OR, 2.0; 95% CI, 1.1 to 3.5; p < 0.02). The prevalence of current asthma was 6.7% for grape farmers and 2% for the control group (difference not significant). All subjects with a current diagnosis of asthma were found to be atopic.

Regarding work-related respiratory symptoms, grape farmers had significantly elevated ORs for work-related sneezing (OR, 2.9; 95% CI, 1.3 to 6.6; p < 0.01), work-related rhinorrhea (OR, 2.9; 95% CI, 1.3 to 6.6; p < 0.01), work-related cough (OR, 3.7; 95% CI, 1.2 to 11.4; p < 0.05), and work-related dyspnea (OR, 3.8; 95% CI, 1.1 to 1.3; p < 0.05), but not for work-related wheezing, compared to the control subjects after adjustment for age, sex, and smoking status.

The prevalence of atopy was calculated to be 64.2% for the group of grape farmers and 38.0% for the control group (OR, 2.2; 95% CI, 1.2 to 3.5; p < 0.01). The proportion of subjects with one or more positive SPT results was significantly greater in the grape farmer group than in the control group (OR, 2.2; 95% CI, 1.3 to 3.8; p < 0.005). Analysis by type of allergen showed a significantly greater proportion of farmers with positive SPT results for pollens compared to the control group (OR, 2.3; 95% CI, 1.3 to 4.1; p < 0.01). More specifically, the most prevalent pollens for which the presence of allergen-specific IgE was demonstrated were as follows: (1) Gramineae mix (30 grape farmers, 25.0%; 8 control subjects, 8.0%; OR, 3.8; 95% CI, 1.7 to 8.8; p < 0.01); (2) C dactylon (25 grape farmers, 20.8%; 10 control subjects, 10.0%; OR, 2.3; 95% CI, 1.3 to 4.1; p < 0.01); and (3) composite mix (20 grape farmers, 16.7%; 3 control subjects, 3.0%; OR, 4.8; 95% CI, 1.3 to 18.2; p < 0.001). According to the results of EIA tests, there were no significant differences regarding allergic sensitization between grape farmers and control subjects.

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